Definition of Loco

Adjective: loco low-kow

Informal or slang term meaning insane, strange, eccentric or stupid
"it used to drive my husband loco";
- balmy [archaic], barmy, bats, batty, bonkers, buggy [N. Amer], cracked, crackers, daft, dotty, fruity, haywire, kooky, kookie, loony, loopy, nuts, nutty, round the bend, around the bend, wacky, whacky, daffy, dippy, nutsy [N. Amer], potty [Brit], daft as a brush [Brit], round the twist [Brit], wacko, cuckoo
Of or relating to locomotion
- locomotive, locomotor

Noun: loco low-kow

A wheeled vehicle consisting of a self-propelled engine that is used to draw trains along railway tracks
- locomotive, engine, locomotive engine, railway locomotive [Brit, Cdn], railroad locomotive [N. Amer]